THE USE OF INTERIM DATA AND DATA MONITORING COMMITTEE RECOMMENDATIONS IN RANDOMIZED CONTROLLED TRIAL REPORTS: FREQUENCY, IMPLICATIONS AND POTENTIAL SOURCES OF BIAS

Abstract Background Interim analysis of accumulating trial data is important to protect Storage Shelf participant safety during randomized controlled trials (RCTs).Data Monitoring Committees (DMCs) often undertake such analyses, but their widening role may lead to extended use of interim analysis or recommendations that could potentially bias trial

Over the decades Europe has become a destination for different Jars groups of migrants, including mobile citizens from the European Union Member States.At the same time European citizens have become more mobile with a growing number of cross-border practices connecting them to places and people abroad through migration, travel, social networks or c

The term reflex epilepsy in reserved for a small subgroup o seizures that occur regularly in response to specific stimuli.Our patient is a 20- year old male, who had pleasure, euphoria, loss of conciousness personal care and generalized tonic- clonic convulstion when he watched TV since ten years.During puberty the patient that self-induced reflex

Atopic dermatitis (AD) is a complex inflammatory skin condition that is not fully understood.Epidermal barrier defects and Th2 immune response dysregulations are thought to play crucial roles in the pathogenesis of the disease.A vicious circle takes place between these alterations, and it can further be complicated by additional genetic and environ